Transgenic & Genome Editing Core Administration

Administrative Oversight

Administrative oversight is provided through the MUSC Division of Lab Animal Resources (DLAR).

Scientific Oversight

Fu-Lei Tang, M.D., Ph.D.

Dr. Tang acts as the Core's Director providing scientific oversight and overseeing the planning and implementation of genome editing and transgenic projects in mice and rats. He is available for consultation prior to each project and responsible for the design, procurement, and in vitro validation of CRISPR reagents, as well as PCR-based genotyping of genetically engineered mice

Generation of Genetically Engineered Mice and Rats – Experimental Work: Genetic engineering in mice and rats involving pronuclear injection and electroporation of single-cell mouse and rat embryos is being performed by Jan Guz.

Assisted Reproductive Technology Services (ARTS):This includes cryo-preservation of mouse sperm and embryos, sperm and embryo resuscitation including in vitro fertilization (IVF), as well as archiving of cryopreserved sperm and embryos. These services are being performed by Jan Guz.