COVID-19 Biorepository

MUSC has established a COVID-19 biorepository that includes samples from patients known to be COVID-19 positive and negative. The samples include DNA/RNA, serum, plasma, PBMCs, nasopharyngeal (NP) swabs used for testing, as well as longitudinal samples from convalescent patients. Because these specimens represent a finite resource, an oversight committee has been formed to review requests to obtain samples.

Currently, the COVID-19 Biorepository contains samples from 221 unique patients. (last updated 10/22/2021)

Application Process

To apply for samples, the following information should be uploaded:

• Names and affiliations of investigators associated with the project
• Funding source for the project
• Type of samples requested, amounts and frequency (if applicable)
• Scientific background and rationale for the project
• Hypotheses and Specific Aims
• Experimental design, including sample size calculation
• Data analysis plan
• Expected outcomes and impacts

COVID-19 Biorepository Request Application

Review of Applications

Applications will be reviewed in accordance with the following criteria:

(1) Availability of samples requested
(2) Overall scientific merit of the study
(3) Feasibility of the study, including statistical significance
(4) Potential impact on the prevention or treatment of COVID-19
(5) Expertise of the investigative team
(6) Involvement of MUSC investigators

Please note the following:

• Only applications received through the REDCap site can be accepted
• Applications will be reviewed on a rolling basis
• Samples will only be released if the relevant IRB/IBC approvals are in place
• A progress report on the study is expected after 6 months

Please note that there is an administrative charge to obtain samples from the COVID-19 Biorepository. Contact Amy Gandy for more information.

*PBMC cell counts are 1.0 x 107/1mL

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Dr. Patrick Flume

Patrick Flume, MD