COVID-19 Biorepository

MUSC has established a COVID-19 biorepository that includes samples from patients known to be COVID-19 positive and negative. The samples include DNA/RNA, serum, plasma, PBMCs, nasopharyngeal (NP) swabs used for testing, as well as longitudinal samples from convalescent patients. Because these specimens represent a finite resource, an oversight committee has been formed to review requests to obtain samples.

Currently, the COVID-19 Biorepository contains samples from 235 unique patients. (last updated 12/21/2022)

Application Process

To apply for samples, please complete the initial REDCap below. The following information will be required to complete the process:

Names and affiliations of investigators associated with the project
PI biosketch
Funding source for the project
Type of samples requested, amounts and frequency (if applicable)
Scientific background and rationale for the project
Hypotheses and Specific Aims
Experimental design, including sample size calculation
Data analysis plan
Expected outcomes and impacts

COVID-19 Biorepository Request Application

RFA to Conduct Research

The RFA To Conduct Research With Biospecimens Obtained from Patients with COVID-19 aims to answer important questions concerning the pathogenesis and sequelae of COVID-19.

View RFA

Review of Applications

Applications will be reviewed in accordance with the following criteria:

(1) Availability of samples requested
(2) Overall scientific merit of the study
(3) Feasibility of the study, including statistical significance
(4) Potential impact on the prevention or treatment of COVID-19
(5) Expertise of the investigative team
(6) Involvement of MUSC investigators

Please note the following:

• Only applications received through the REDCap site can be accepted
• Applications will be reviewed on a rolling basis
• Samples will only be released if the relevant IRB/IBC approvals are in place
• A progress report on the study is expected after 6 months

Please note that there is an administrative charge to obtain samples from the COVID-19 Biorepository. Contact Amy Gandy for more information.

*PBMC cell counts are 1.0 x 10⁷/1mL