MUSC operates under Federalwide Assurances (FWAs) in accordance with Subpart A 46.103a which requires any institution engaged in non-exempt human subjects research conducted or supported by HHS to submit a written assurance of compliance with OHRP.

Renewal is required every 5 years.  Any updates made to the FWAs begins a new 5-year effective period.

IRB Registrations

All  of the MUSC IRBs listed under the FWAs are registered electronically in accordance with 45 CFR 46,ยง 501-505.  Renewal is required every 3 years.  Any updates  made to the IRB registration begins a new 3-year registration period

Each IRB registered under an FWA has a unique registration number.  The IRB registration numbers for the MUS's IRB are:

IRB00000027 Medical U South Carolina IRB 1
IRB00000028 Medical U South Carolina IRB 2
IRB00001377 Medical U South Carolina IRB 3

The Institution or Organization (IORG) number is a unique number assigned by OHRP to an institution or organization the first time an institution or organization registers an IRB.  The IORG number for the MUSC IRB is IORG 0000020.

This registration is listed under our entries on the OHRP Database.

MUSC is the University Affiliate IRB for the Ralph H. Johnson Veterans Affairs Medical Center. The VA operates under FWA #00001591. 

Memorandum of Understanding Between the Ralph H. Johnson VA Medical Center and the Medical University of South Carolina. Effective October 2, 2020