DURC Agents and Experiments
What Agents are subject to the Policy?
Research that directly involves any of the following 15 agents and toxins*
Avian influenza virus (highly pathogenic)
Botulinum neurotoxin (in any quantity)
Foot-and-mouth disease virus
Reconstructed 1918 Influenza virus
Toxin-producing strains of Clostridium botulinum
Variola major virus
Variola minor virus
*Except attenuated strains of the agents that are excluded from the Select Agent list and inactive forms of botulinum neurotoxin
What type of experiments are subject to the Policy?
- Enhances the harmful consequences of the agent or toxin
- Disrupts immunity or the effectiveness of an immunizationagainst the agent or toxin without clinical and/or agriculturaljustification
- Confers to the agent or toxin resistance to clinically and/oragriculturally useful prophylactic or therapeutic interventionsagainst that agent or toxin or facilitates their ability to evadedetection methodologies
- Increases the stability, transmissibility, or the ability todisseminate the agent or toxin
- Alters the host range or tropism of the agent or toxin
- Enhances the susceptibility of a host population to the agentor toxin
- Generates or reconstitutes an eradicated or extinct agent ortoxin listed in the policy
For more information about the U.S. Government DURC Policy, click here.