Nuclear Magnetic Resonance Facility

Nuclear magnetic resonance (NMR) spectroscopy is a solution-based technique used to probe the structure and dynamics of molecules, ranging from small molecules to proteins. The NMR facility at MUSC comprises three NMR spectrometers with field strengths of 400 and 600. The 400 MHz spectrometer is used mainly for small molecule analysis and has two broadband probes. The 600 MHz spectrometer is primarily used for biomolecular research, including solving high-resolution structures of macromolecules, measuring drug/protein interactions and metabolomics. The facility is housed within a custom-built laboratory on the first floor of the Drug Discovery Building.

The NMR facility can be accessed in two ways:

1. Trained users can access the spectrometers on an hourly-fee basis.
2. For those without NMR expertise, experiments can be performed by the Facility Manager, in which case additional fees will apply to cover time spent.

For extended projects, a percentage effort coverage of the Facility Manager can be negotiated.

Contact Information

Director: Patrick M. Woster, Ph.D.
woster@musc.edu

Address:
Department of Drug Discovery and Biomedical Sciences
College of Pharmacy
DD 404, MSC 139
70 President Street
Charleston, SC 29425