Pilot Grants Program

SCTR supports a number of different mechanisms that represent the translational spectrum - from basic science to population health - including patient-centered and community-engaged research. Early Career Investigators are strongly encouraged to apply for pilot grants on their pathway to research independence.

Discovery and High-Innovation High Reward grants are part of the PTC portfolio. Other pilot grants are offered in collaboration with the Team Science and Community Engagement Programs and the South Carolina Telehealth Alliance. Some opportunities have rolling submission deadlines and others have specific requests for applications (RFAs) issued throughout the year.

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The MUSC-Siemens Photon Counting Computed Tomography Pilot Project Grant is now requesting applications. Applications are due by 5:00 p.m. EST, March 22, 2022.

MUSC-Siemens Photon Counting Computed Tomography Pilot Project Grant


This funding mechanism solicits grant applications proposing novel, advanced, or enhanced uses of Siemens Photon Counting Computed Tomography (PCCT) technology. Co-sponsored by the MUSC Office of Innovation, Siemens Healthineers, and South Carolina Clinical and Translational Research (SCTR) Institute.

(Budget $50,000; 12 months) 

RFA and Application Form

K-Awardee & Predoctoral Trainee Collaborative Grant


This new grant mechanism seeks to promote a team-based collaborative translational research project between a current or recently graduated K-awardee and a predoctoral trainee while enhancing team science and mentoring. The project could involve basic research, clinical research, and/or community/population health research approaches for the purposes of collecting critical preliminary data for submission of extramural grant applications, fellowship applications and to publish, disseminate and/or implement research findings.

(Budget $50,000; 2 years) 

Discovery Grants


SCTR's Discovery Grants facilitate new and innovative, high-impact translational research. The primary objectives are to support new and innovative, scientifically meritorious projects to collect critical preliminary data for submission of extramural grant applications and to publish research findings. We place a premium on cross-disciplinary translational team science and new collaborations.

(Budget $25,000; 12 months)

SCTR Team Science Pilot Project Grants


Team Science is focused on understanding and enhancing the processes and outcomes of teams in healthcare, education and research. A key goal of the Team Science pilot project grants is to generate new knowledge about factors that maximize the efficiency, productivity, and effectiveness of teams and/or new information about processes by which clinical and scientific teams organize, communicate, and function collaboratively.

Potential projects may focus on, but are not limited to, direct measurement of the impact of teamwork on research productivity, scientific innovation, patient outcomes, patient safety, cost-effectiveness of health care or research practice, health professional educational, training and clinical care outcomes. Projects may also focus on team development approaches, assessment tools, and factors that contribute to high and/or low functioning teams in healthcare and research settings.

(Budget $15,000; 12 months)

Telehealth Pilots


Telehealth pilot grants support South Carolina clinicians and researchers in their efforts to develop innovative, telehealth projects that aim to accelerate the adoption, utilization, and investigation of telehealth interventions in South Carolina. Applicants are strongly encouraged to take a cross-disciplinary translational team approach and include investigators from more than one South Carolina institution/organization.

(Budget $25,000; 12 months)

Cristin Adams, DO, Assistant Professor
MUSC College of Medicine, Family Medicine

Project Title: Iterative intervention development and feasibility testing of a smoking cessation e-visit for individuals experiencing homelessness


Lauren Demosthenes, MD, Clinical Assistant Professor
Prisma Health-Upstate
USC School of Medicine, Obstetrics and Gynecology

Project Title: A comparison of standard office based postpartum BP monitoring to a text based remote self BP monitoring program in the management of maternity patients with a hypertensive disorder of pregnancy


Claire Macgeorge, MD, MSCR, Assistant Professor
MUSC College of Medicine, Pediatrics

Project Title: Improving Pediatric ADHD Management with Virtual Check-ins: A Study of Utilization and Acceptability


Nandita Nadig, MD, MSCR, Assistant Professor
MUSC College of Medicine, Pulmonary and Critical Care

Project Title:  Stressors of Inter-ICR Transfer: Family Centered Care through Telehealth

High Innovation-High Reward Pilots


This funding mechanism supports new and cross-disciplinary pilot projects that propose substantial development of intellectual property and/or commercialization opportunities. Applications are accepted on a "rolling" basis and will be reviewed within 3-4 weeks of submission. When an application is submitted please notify Dayan Ranwala, Ph.D. by email.

(Budget $10,000; 12 months)

RFA and Application Form

Current High Innovation-High Reward Projects

Robert Adams, M.D.

Project Title: Optimizing Zeriscope for PTSD Clinical Studies (OPUS)


David Turner, Ph.D.
Pathology & Laboratory Medicine

Project Title: Characterization of race specific primary prostate cancer cell lines for commercialization 



Other Funding