Scientific Environment

MUSC Overview

Founded in 1824 in Charleston, the Medical University of South Carolina is South Carolina’s only comprehensive academic health science center. MUSC educates and trains more than 3,200 students and 900 residents in six colleges (Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing, and Pharmacy) and has nearly 26,000 team members, including approximately 1,500 faculty members. As the largest non-federal employer in Charleston, the university and its affiliates have collective annual budgets of $5.9 billion, with an annual economic impact of more than $5.6 billion and annual research funding of more than $300 million (2023). As the clinical health system of the Medical University of South Carolina, MUSC Health is comprised of some 2,700 beds, nearly 750 care locations, the MUSC College of Medicine, the physicians’ practice plan, and more than 350 telehealth locations. Additionally, MUSC Health operates (owned and equity stake) sixteen hospital locations situated in Charleston, Chester, Fairfield, Florence, Kershaw, Lancaster, Marion, Orangeburg, Richland and Williamsburg counties – designated as the MUSC Regional Health Network. In 2024, for the 10th consecutive year, U.S. News & World Report named MUSC Health the number one hospital in South Carolina.

Back to Top


The Office of Innovation serves as a catalyst for innovations that ultimately create value for the MUSC Enterprise, patients, and students. The office is charged with providing leadership and coordination of a robust innovation ecosystem supporting both intrapreneurship and entrepreneurship across the tripartite mission. The office aims to build a culture and capacity for innovation that is nationally recognized and to facilitate the development of processes, technologies and strategies that produce real-world beneficial impact for those served.

Our Partners

Additional Partnerships

Discover more about our partnerships and how they’re helping MUSC change what’s possible.

Back to Top

Research Environment

MUSC is the center of the state’s largest medical complex, located on the west side of Charleston, SC. A free-standing academic health center, MUSC is the only tertiary/quaternary care referral center for the entire state. Within a four-block radius of MUSC are the Ralph H. Johnson VA Medical Center, Charleston County Health Department, Roper/St. Francis Healthcare (the area’s largest community hospital), and numerous health professional offices and services.

MUSC has been at its present site on the Charleston peninsula since 1913, and currently occupies more than 80 acres and 89 buildings. Research buildings at MUSC include the Basic Sciences Building, a 7-story, 332,000 sqft laboratory complex that houses MUSC’s basic science departments; Darby Children’s Research Institute, a 7-story, 122,000 sqft building housing 14 multidisciplinary lab-based research programs, adjoining the Basic Science Building; the Thurmond Biomedical Research Building, a 7-story, 180,000 sqft building that contains the Gazes Cardiac Research Institute as well as MUSC and VA research labs and shared facilities; and Walton Research Building, an 8-story, 56,600 sqft building housing research laboratories for Pathology, Otolaryngology-Head & Neck Surgery, and Pharmaceutical Sciences. Two new research buildings opened in Fall 2011. Connected to the Basic Science Building via a pedestrian sky-bridge, the Drug Discovery and Bioengineering Buildings add 220,000 sqft for translational research, research training, and in vivo experimentation. Buildings that include significant research laboratory space, as well as clinical facilities, include the Storm Eye Institute with a 40,000 sqft Vision Research Center; and the Hollings Cancer Center with more than 200,000 sqft including 98,000 sqft dedicated to laboratory-based research.

All laboratory investigators have well-equipped modern laboratories with suitable space for students. Appropriate glassware and sterilization facilities are provided. All researchers at MUSC have access to shared equipment and standard resources such as ultra-low freezers, centrifuges, scintillation counters, and cold, warm, light-controlled, and tissue culture rooms.

Back to Top

Clinical Environment

MUSC Health, the clinical enterprise of the Medical University of South Carolina (MUSC), is dedicated to the pursuit of changing what’s possible in health care. The innovations and leadership of this integrated health care system are evident, not only in the hospitals (University Hospital; Ashley River Tower, a cardiovascular, gastrointestinal, and cancer specialty hospital; the Institute of Psychiatry; the Storm Eye Institute; and Children’s Hospital) on the downtown Charleston campus, but shared with the sixteen hospitals (owned and equity stake) within the Regional Health Network (situated in Charleston, Chester, Fairfield, Florence, Kershaw, Lancaster, Marion, Orangeburg, Richland and Williamsburg counties), more than 750 Care locations, clinical affiliations with numerous health care partners, and a robust telehealth network. MUSC Health serves more than two million patients annually, and its specialized care teams consistently rank among the best in the country. MUSC Health delivers transformational care shaped by world-class clinicians, health scientists, and educators who provide leading-edge care while developing the next generation of innovative health care leaders.

The MUSC Medical Center is a key component of MUSC Health. This premier health sciences center is at the forefront of the latest advances in medicine and includes South Carolina’s #1 and most preferred hospital (as ranked by U.S. News & World Report on its Best Hospitals 2014-2024 and the National Research Corporation respectively), a NCI-designated Cancer Center, a Level I Trauma Center, and South Carolina’s only nationally recognized children’s hospital. The Research Mission is to provide excellence in patient care, teaching, and research in an environment that is respectful of others, adaptive to change, and accountable for outcomes. The Medical Center advances biomedical knowledge by serving as a setting for clinical and translational research, providing resources to conduct research, and offering opportunities for patients to participate appropriately in research and treatment protocols.

The MUSC Medical Center is licensed by the South Carolina Department of Health and Environmental Control and has Joint Commission accreditation with the “Gold Seal of Approval,” attesting that the accredited organization has demonstrated compliance to the most stringent standards of performance. MUSC undergoes an extensive unannounced on-site Joint Commission review at least once every three years. The MUSC Medical Center has earned numerous Joint Commission Special Quality Awards including Advanced Inpatient Diabetes Certification (2017), Advanced Comprehensive Stroke Center Certification (2016), Gold Plus ‘Get with the Guidelines for Stroke’ (2013) and Heart Failure (2014), and American Cancer Society National Surgical Quality Improvement Program (2012). MUSC has additional accreditation for Behavioral Health Care. For the 17th consecutive year (2016/2017), MUSC received the Consumer Choice Award from the National Research Corporation (NRC) as one of the nation’s top hospitals. MUSC is the only medical center in the state that offers transplant programs for heart, pancreas, kidney-pancreas, small bowel and liver (including living donor procedures for liver transplantation). U.S. News & World Report ranked MUSC as the top hospital in South Carolina for 2024-2025 and among the best in the country for the treatment of ENT disorders and obstetrics & gynecology. Eighteen other MUSC Health-Charleston Division (University Medical Center) programs are considered “high-performing” specialties, procedures, or conditions and include cancer, gastroenterology & GI surgery, rheumatology, urology, aortic valve surgery, colon cancer surgery, gynecological cancer surgery, heart attack, heart bypass surgery, heart failure, hip replacement, kidney failure, knee replacement, leukemia, lymphoma & myeloma, lung cancer surgery, pneumonia, prostate cancer surgery and stroke. In addition, MUSC Health-Columbia high performing specialties include: heart attack, heart bypass surgery, heart failure and hip replacement. MUSC Health-Florence Division is designated “high performing” in chronic obstructive pulmonary disease (COPD), heart attack, heart failure, kidney failure, and stroke. MUSC Health-Orangeburg Division is recognized for heart failure treatment. MUSC is among seven percent of U.S. hospitals to earn Magnet Recognition by the American Nurses Credentialing Center for quality patient care, nursing excellence and innovations in professional nursing practice.

Additional Awards

Find out more about the many awards and recognition MUSC Health has received.

Back to Top

Regional Health Network

MUSC Health’s expansion to clinical systems across regions of South Carolina makes it possible to offer research and clinical trials participation opportunities to a large, diverse population, including individuals living in rural areas. Counties within the MUSC Regional Health Network (RHN) include Charleston, Chester, Fairfield, Florence, Kershaw, Lancaster, Marion, Orangeburg, Richland and Williamsburg. Key MUSC RHN medical centers beyond Charleston county are described below.

Back to Top

Office, Computer & Information Resources

Office areas at MUSC are well lighted ventilated and appointed for scholarly activities, paperwork, and modes of communication (voice, data, analog, digital, etc.) that are common and appropriate at a contemporary health professional university and academic medical center. Competent support staff and all standard office services and software are readily available to facilitate the academic and scientific activities of faculty, trainees, and technical staff.

Laboratories and offices typically have several networked PC and Apple computers and laser printers. The MUSC campus offers network access to computerized clinical data management systems, outpatient electronic medical records, Lanvision, Access Anywhere, IDX registration system, and the integrated laboratory system. Standard statistical software includes Epistat, SAS, SPSS, S-Plus, and M-Plus. DXCG and ACG software are available for patient case mix analysis. Office 365 is the standard suite of office tools/software. All data are locally backed up through password-protected Apple Time Machine hard drives and/or a Novell server while institutional protocols ensure long-term data security and protection.

Back to Top

NIH Policy on the Use of Hypertext

NIH Policy on Use of Hypertext in NIH Grant Applications: Hyperlinks and URLs are only allowed when specifically noted in funding opportunity announcement (FOA) and form field instructions. The use of hyperlinks is typically limited to citing relevant publications in biosketches and publication lists.

Visit ORD's Grant Writing Toolkit (Login Required) to access additional Scientific Environment templates customized for specific grant mechanisms.

Back to Top