Skip to main content

SCTR: Who We Are

About SCTR

The South Carolina Clinical & Translational Research (SCTR) Institute is part of a national network established by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). Our goal is simple: to provide the expertise necessary to bridge the gap between biomedical discovery and real‑world solutions that improve people’s health. We connect researchers, clinicians, and communities with the support and resources they need to translate their research innovations into better treatments, better care, and better health for everyone.

Our Focus

SCTR is focused on advancing human health by strengthening translational science, the field dedicated to moving discoveries into real‑world impact more efficiently.

Translational Research vs. Translational Science

Through our programs, services, and expertise, SCTR helps research teams overcome common barriers in conducting translational research and strengthens the scientific process itself.

Translational Research

Pushing one promising idea toward real‑world impact

Translational research is the hands‑on work of taking a promising idea from the lab, clinic, or community and steadily shaping it into something that can genuinely help people, like a new test, treatment, or prevention strategy. It’s about moving step‑by‑step from discovery to rigorous clinical study to adoption into everyday care.

Translational Science

Strengthening the entire pathway so every idea can make an impact

Translational science is about figuring out how to move good ideas in health and medicine into real‑world solutions more efficiently. It closely examines the steps where progress often gets stuck, such as improving how studies are designed or making it easier for communities to benefit from new advances, and then works to remove those obstacles. Instead of focusing on a single disease or condition, the goal of translational science is to make the entire journey from discovery to patient care more efficient and reliable, so that promising research can make a meaningful difference in everyday health.

Programs & Services

Research resources, services, and activities are organized in several programmatic areas that span all stages of translational research, from discovery to implementation. SCTR also includes formal predoctoral (T32) training and career development (K12) components.

Services & Consultations

Research Nexus

The Research Nexus facilitates patient-oriented research through several fee-based research services, including research coordination and management, clinical nursing, and laboratory studies.

Learn More

SUCCESS Center

The Support Center for Clinical & Translational Science (SUCCESS) is staffed by a team of experts who provide research navigation and free consultations to clinical and translational research investigators and stakeholders across South Carolina.

Learn More

SPARCRequest

Consultations and services are requested, reviewed, and tracked using the SPARCRequest system, which was developed by SCTR. This request engine and work fulfillment portal provides a storefront for all core research services and resources at MUSC. SPARCRequest is used by many other CTSA programs across the United States.

Learn More

Our Collaborators

SCTR’s robust network of collaborators includes academic, health care, and community-based organizations across the state.

Community Advisory Board

  • US Department of Agriculture
  • South Carolina Area Health Education Consortium (AHEC)
  • South Carolina Institute of Medicine & Public Health
  • South Carolina Research Authority
  • South Carolina Office of Rural Health

SCTR contributes to national efforts that advance clinical and translational science and research.

Learn More

Community Collaborators

  • Clemson University
  • National Telehealth Center of Excellence
  • Department of Veterans Affairs Community Advisory Board

Several SC Organizations engage with SCTR to provide insight into community priorities, guide community-engaged research, and serve as liaisons with community stakeholders.

Collaborating Institutions

  • Medical University of South Carolina
  • South Carolina State University
  • University of South Carolina

National Collaborators

  • Clinical and Translational Science Awards (CTSA) Program
  • CTSA Coordination, Communication, and Operations Support (CCOS)
  • Helping End Addiction Long Term (HEAL)
  • National Institutes of Health (NIH)
  • Patient-Centered Outcomes Research Institute (PCORI)
  • SPARCRequestTrial Innovation Network (TIN)

SCTR Leadership

Co-Principal Investigators:

Patrick Flume, M.D.

flumepa@musc.edu

 

Kathleen Brady, M.D., Ph.D.

bradyk@musc.edu

SCTR Administrative Teams

Administration, Finance & Evaluation Teams

Royce Sampson, MSN, RN, CRA
Primary Administrator, Chief Operations Officer & Finance Director
sampsonr@musc.edu

Debi Cain
Finance and Grants Administrator
caind@musc.edu

Stephanie Gentilin, MA, CCRA
Director, SUCCESS Center
mamaysl@musc.edu

Tammy Loucks, MPH, DrPH
Science Development Officer
louckst@musc.edu

Theresa Milne
Office Manager
milne@musc.edu

Danielle Hutchison, MAOM
Communications Manager
hutchiso@musc.edu

Sydney Bollinger, MS
Special Projects Coordinator
bollinger@musc.edu

Sophia Barry Gordon, MS
Science Writing & Communications Program Coordinator 
barrygor@musc.edu

Debi Cain | Finance and Grants Administrator
caind@musc.edu

Kim Dalrymple | Grants Administrator
dalrympl@musc.edu

Eryn Varano
| Service Center Manager
varanoe@musc.edu

Karl D. Walsh | Senior Grants Administrator
walshk@musc.edu

Susan Waltz | Administrative Coordinator II
waltzs@musc.edu

The Evaluation & Quality Improvement (EQI) program within SCTR uses evaluation and quality improvement processes to increase the effectiveness and efficiency of clinical and translational research. In addition to collecting, analyzing, synthesizing, and reporting evaluation and quality improvement data, the EQI team works closely with SCTR programs to facilitate their use of these data in their scientific efforts. The EQI program's specific goals are:

  • To work with SCTR personnel to monitor SCTR activities and provide timely feedback to the program directors, faculty, and administrators responsible for SCTR to improve quality and increase efficiency.
  • To determine the effectiveness of SCTR in achieving both short- and long-term goals.
  • To work with SCTR programs and cores to build their capacity for evaluation and quality improvement.

EQI Evaluation Theories

  • Developmental Evaluation (DE) allows for the evolution of evaluation methods and metrics within emergent environments and for rapid-cycle assessments for program adaptation to system and community needs.
  • Utilization-Focused Evaluation (UFE) specifies the intended “meaningful use” of evaluation outcome metrics by the targeted evaluation users.
  • Theories of Constraints Lean Six Sigma (C-LSS) combines primary Quality Improvement (QI) theories and methodologies to formulate an approach in which system constraints are identified (TOC), waste is eliminated from the process (Lean), and the variability within the process becomes stabilized (Six Sigma).
  • Integrations of Team Science-Social Network Analysis (SNA) and Relational Coordination (RC) Theories – SNA is the mapping and measuring of relationships and flows between people, groups, organizations, and other connected information/knowledge entities. The nodes in the network are the people and groups, while the links show relationships or flows between the nodes. RC describes the interdependence between tasks but also between the people who perform those tasks, using three Relational measures (shared goals, shared knowledge, mutual respect) and four Communication measures (frequency, timeliness, accuracy, problem-solving).

EQI Evaluation Model

Results-Based Accountability (RBA) 

SCTR RBA matrix has four dimensions – program effort, program effects, quantity of results, and quality of results. Evaluation questions can be grouped into seven different categories:

  1. Effort: How much did SCTR and each of its programs do?
  2. Quality: How well did they do it (e.g., fidelity to best practice)?
  3. Relevance to Target Population: Do SCTR and its programs meet the needs and priorities of the target group? How were those needs identified? Were appropriate stakeholders engaged in planning, implementation, and assessment of results?
  4. Efficiency: Have SCTR and its programs reduced, as appropriate, cost per person, cost per unit of activity, or time to completion with no loss of quality?
  5. Effectiveness: To what extent have SCTR activities led to progress in accomplishing Institute and program aims?
  6. Outcome: To what extent have SCTR and its programs accomplished their aims? Were there any other unintended positive or negative outcomes?
  7. Sustainability: To what extent have SCTR and its programs led to long-term system change?

Contact the Evaluation Team

Jillian Harvey, Ph.D.
Evaluation Program Director
harveyji@musc.edu

Rechelle Paranal, MSW, MA
Director of Planning and Research
paranal@musc.edu

CTSA Program

SCTR is funded in part through the Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences, a National Institute of Health.

Additional support for SCTR is provided by:

  • Medical University of South Carolina (MUSC) College of Medicine
  • Hollings Cancer Center
  • MUSC Office of the Vice President for Academic Affairs & Provost
  • MUSC Health Authority

Cite the Grant

Find guidance for award citation and public access compliance for SCTR’s Clinical and Translational Science Award (CTSA) on SCTR's internal web page (login required).

Visit Cite the Grant web page

Locations

SCTR Research Nexus

96 Jonathan Lucas Street
Suite: 214
MSC Code: 195
Charleston, SC 29425
Directions

SCTR Institute

Roper MOB
125 Doughty Street
Suite: 140
MSC Code: 195
Charleston, SC 29403

Directions

Contact Us

SCTR SUCCESS Center

843-792-8300
SUCCESS@musc.edu