Pilot and Feasibility Projects in Digestive and Liver Diseases

Funding Opportunity for Pilot and Feasibility Projects in Digestive and Liver Diseases

 

Key Dates

  • Letter of Intent Due: June 8, 2020
  • Invitation to Submit Full Application: June 18, 2020
  • Full Application Due: July 16, 2020

The MUSC COBRE in Digestive & Liver Diseases (MUSC CDLD) and the MUSC Digestive Diseases Research Core Center (MUSC DDRCC) invites investigators to apply to the Pilot and Feasibility (P/F)Funding Program. The overall objective of the P/F Program is to support MUSC investigators who are interested in pursuing basic, clinical, or translational research of diseases that affect the liver and/or gastrointestinal system. Proposed projects should have a high likelihood of progression to extramural funding and directly utilize one or more of the CDLD and/or DDRCC Core Resources. Applications that develop or strengthen collaborative interactions amongst the MUSC digestive disease research community are highly encouraged. The P/F Program will fund up to four grants at up to $50,000 indirect costs per year. P/F awardees may be invited to apply for the second year of funding through a competitive renewal.

Pilot Project Categories

The P/F Program will support three general grant categories, with promising new investigators given the highest priority. Proposed projects must involve digestive and/or liver disease research.

Type I. Discovery grants for new investigators

MUSC faculty at the Assistant or Associate Professor level who have not had previous extramural independent support as Principal Investigator (e.g. NIH R01, P01 subproject, or equivalent) are eligible. Those with current extramural independent support as Principal Investigator are ineligible. Investigators supported by Career Development or Fellowship awards (K01, K08, or similar) are considered eligible for Type I funding. Applicant’s funded through the CDLD are expected to identify a mentor who is an established investigator in the digestive disease field.

Type II. New direction grants for faculty who are established in a field other than digestive and liver disease

MUSC faculty who have previously or are currently funded through the NIH or similar mechanism and are interested in applying their expertise to digestive and/or liver disease research. Faculty can be of any rank but should have a record of accomplishment in their chosen field. The proposed project cannot overlap with any ongoing funded project.

Type III.  Feasibility grants for faculty who are established digestive and liver disease researchers

MUSC faculty who wish to explore innovative new ideas that represent a significant departure from their ongoing funded projects. Justification of the new direction is essential. Faculty can be of any rank but should have a record of accomplishment in their chosen field. The proposed project cannot overlap with any ongoing funded project.

Application Process

Applicants should submit a letter of intent (LOI) via email to Caroline Westwater.

LOIs should be submitted as a single PDF. The deadline for LOI submission is June 8, 2020.

The LOI should include:

  • Descriptive title of the proposed research.
  • Pilot grant category (Type I, II, or III) for which the applicant wishes to apply.
  • Name, email address, and telephone number of the PI. Investigators may submit one application as PI per funding cycle and may serve as a co-investigator on multiple applications.
  • Names of the investigative team, their academic titles, primary department, and proposed role on the project. For Type I applications, a primary mentor must be identified.
  • NIH style biosketch for each member of the investigative team (include ongoing and completed research projects from the past three years).
  • A specific aims page describing the scientific premise, project goal, approach, and planned use of Core Resources (no more than one page in length). Information on available Core Resource can be found at the MUSC CDLD and MUSC DDRCC websites.

After review of the LOI, successful applicants will be asked to submit a full application, consisting of the following components: Project Summary, Specific Aim page (1-page limit), Research Proposal (4-page limit), Literature Cited, Budget and Justification, NIH Biosketch for each investigator, and list of current and pending Other Support for each investigator. Specific details regarding the full application process will be provided to successful applicants.

Questions regarding this RFA can be directed to Caroline Westwater (westwatc@musc.edu), Stephen Duncan (duncanst@musc.edu), or Don Rockey (rockey@musc.edu).

Additional Information

MUSC COBRE in Digestive & Liver Disease (MUSC CDLD)

MUSC Digestive Diseases Research Core Center (MUSC DDRCC)