Recent Publications

1: Richards DJ, Li Y, Kerr CM, Yao J, Beeson GC, Coyle RC, Chen X, Jia J, Damon
B, Wilson R, Starr Hazard E, Hardiman G, Menick DR, Beeson CC, Yao H, Ye T, Mei
Y. Human cardiac organoids for the modelling of myocardial infarction and drug
cardiotoxicity. Nat Biomed Eng. 2020 Apr;4(4):446-462. doi:
10.1038/s41551-020-0539-4. Epub 2020 Apr 13. PubMed PMID: 32284552.

2: Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP,
Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC,
Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen
B, Mehrotra S. Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs
T Cells to Limit Anti-tumor Activity. Cell Rep. 2019 Aug 13;28(7):1879-1893.e7.
doi: 10.1016/j.celrep.2019.07.044. PubMed PMID: 31412253; PubMed Central PMCID:
PMC6889821.

3: Cameron RB, Peterson YK, Beeson CC, Schnellmann RG. Author Correction:
Structural and pharmacological basis for the induction of mitochondrial
biogenesis by formoterol but not clenbuterol. Sci Rep. 2019 May 1;9(1):6790. doi:
10.1038/s41598-019-42463-9. PubMed PMID: 31043635; PubMed Central PMCID:
PMC6494870.

4: Ishii M, Beeson G, Beeson C, Rohrer B. An improved method for isolation of
mitochondria from cell lines that enables reconstitution of calcium-dependent
processes. Anal Biochem. 2019 Jul 15;577:52-58. doi: 10.1016/j.ab.2019.04.012.
Epub 2019 Apr 22. PubMed PMID: 31022379; PubMed Central PMCID: PMC6582631.

5: Christie CF, Fang D, Hunt EG, Morris ME, Rovini A, Heslop KA, Beeson GC,
Beeson CC, Maldonado EN. Statin-dependent modulation of mitochondrial metabolism
in cancer cells is independent of cholesterol content. FASEB J. 2019
Jul;33(7):8186-8201. doi: 10.1096/fj.201802723R. Epub 2019 Apr 5. PubMed PMID:
30951369; PubMed Central PMCID: PMC6593894.

6: Il'yasova D, Kinev A, Gregoire R, Beeson CC. A Cell-Based Approach to Study
the Associations Between Mitochondrial Health, Early Life Exposures, and
Consequent Health Outcomes. Front Public Health. 2019 Mar 13;7:36. doi:
10.3389/fpubh.2019.00036. eCollection 2019. PubMed PMID: 30918888; PubMed Central
PMCID: PMC6424859.

7: Qie S, Yoshida A, Parnham S, Oleinik N, Beeson GC, Beeson CC, Ogretmen B, Bass
AJ, Wong KK, Rustgi AK, Diehl JA. Targeting glutamine-addiction and overcoming
CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nat
Commun. 2019 Mar 21;10(1):1296. doi: 10.1038/s41467-019-09179-w. PubMed PMID:
30899002; PubMed Central PMCID: PMC6428878.

8: Cameron RB, Gibbs WS, Miller SR, Dupre TV, Megyesi J, Beeson CC, Schnellmann
RG. Proximal Tubule β (2)-Adrenergic Receptor Mediates Formoterol-Induced
Recovery of Mitochondrial and Renal Function after Ischemia-Reperfusion Injury. J
Pharmacol Exp Ther. 2019 Apr;369(1):173-180. doi: 10.1124/jpet.118.252833. Epub
2019 Feb 1. PubMed PMID: 30709866.

9: Jing R, Corbett JL, Cai J, Beeson GC, Beeson CC, Chan SS, Dimmock DP, Lazcares
L, Geurts AM, Lemasters JJ, Duncan SA. A Screen Using iPSC-Derived Hepatocytes
Reveals NAD(+) as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep.
2018 Nov 6;25(6):1469-1484.e5. doi: 10.1016/j.celrep.2018.10.036. PubMed PMID:
30404003; PubMed Central PMCID: PMC6289059.

10: Chatterjee S, Chakraborty P, Daenthanasanmak A, Iamsawat S, Andrejeva G,
Luevano LA, Wolf M, Baliga U, Krieg C, Beeson CC, Mehrotra M, Hill EG, Rathmell
JC, Yu XZ, Kraft AS, Mehrotra S. Targeting PIM Kinase with PD1 Inhibition
Improves Immunotherapeutic Antitumor T-cell Response. Clin Cancer Res. 2019 Feb
1;25(3):1036-1049. doi: 10.1158/1078-0432.CCR-18-0706. Epub 2018 Oct 16. PubMed
PMID: 30327305; PubMed Central PMCID: PMC6361669.

11: Gibbs WS, Collier JB, Morris M, Beeson CC, Megyesi J, Schnellmann RG.
5-HT(1F) receptor regulates mitochondrial homeostasis and its loss potentiates
acute kidney injury and impairs renal recovery. Am J Physiol Renal Physiol. 2018
Oct 1;315(4):F1119-F1128. doi: 10.1152/ajprenal.00077.2018. Epub 2018 May 30.
PubMed PMID: 29846105; PubMed Central PMCID: PMC6230742.

12: Herr DJ, Baarine M, Aune SE, Li X, Ball LE, Lemasters JJ, Beeson CC, Chou JC,
Menick DR. HDAC1 localizes to the mitochondria of cardiac myocytes and
contributes to early cardiac reperfusion injury. J Mol Cell Cardiol. 2018
Jan;114:309-319. doi: 10.1016/j.yjmcc.2017.12.004. Epub 2017 Dec 7. PubMed PMID:
29224834; PubMed Central PMCID: PMC5846104.

13: Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP,
Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball
L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI,
Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S.
CD38-NAD(+)Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell
Metab. 2018 Jan 9;27(1):85-100.e8. doi: 10.1016/j.cmet.2017.10.006. Epub 2017 Nov
9. PubMed PMID: 29129787; PubMed Central PMCID: PMC5837048.

14: Gibbs WS, Garrett SM, Beeson CC, Schnellmann RG. Identification of dual
mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial
biogenesis. Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F260-F268. doi:
10.1152/ajprenal.00324.2017. Epub 2017 Oct 18. PubMed PMID: 29046298; PubMed
Central PMCID: PMC5866450.

15: Trager NNM, Butler JT, Harmon J, Mount J, Podbielska M, Haque A, Banik NL,
Beeson CC. A Novel Aza-MBP Altered Peptide Ligand for the Treatment of
Experimental Autoimmune Encephalomyelitis. Mol Neurobiol. 2018 Jan;55(1):267-275.
doi: 10.1007/s12035-017-0739-4. PubMed PMID: 28889362; PubMed Central PMCID:
PMC5808857.

16: Cameron RB, Peterson YK, Beeson CC, Schnellmann RG. Structural and
pharmacological basis for the induction of mitochondrial biogenesis by formoterol
but not clenbuterol. Sci Rep. 2017 Sep 5;7(1):10578. doi:
10.1038/s41598-017-11030-5. Erratum in: Sci Rep. 2019 May 1;9(1):6790. PubMed
PMID: 28874749; PubMed Central PMCID: PMC5585315.

17: Thaxton JE, Wallace C, Riesenberg B, Zhang Y, Paulos CM, Beeson CC, Liu B, Li
Z. Modulation of Endoplasmic Reticulum Stress Controls CD4(+) T-cell Activation
and Antitumor Function. Cancer Immunol Res. 2017 Aug;5(8):666-675. doi:
10.1158/2326-6066.CIR-17-0081. Epub 2017 Jun 22. PubMed PMID: 28642246; PubMed
Central PMCID: PMC5585019.